Study Shows Consistent Evidence of Axonal Injury Following A Single TBI For Years After Injury
American Academy of Neurology publishes an important study showing consistent evidence of axonal injury following a single TBI for years after injury using multiple measures, including a blood biomarker, MRI/DTI and volumetric analysis, and functional tests
On July 8, 2020 the American Academy of Neurology published an important study advancing our understanding of, and ability to diagnose, traumatic brain injury (TBI). The study, Shahim P, Politis A, van der Merwe A, et al. Time course and diagnostic utility of NfL, tau, GFAp, and UCH-L1 in subacute and chronic TBI was published online ahead of print, 2020 Jul 8 in Neurology. Funding for the study was provided by the National Institutes of Health and the Department of Defense (Center for Neuroscience and Regenerative Medicine.)
The authors of the study conclude as follows:
“ In summary, these findings suggest that a single mild to moderate TBI may cause long-term neuroaxonal degeneration and astrogliosis/activation.”